Different Kinds of Advanced Prostate Cancer

Prostate cancer that gets worse or spreads despite treatment to lower testosterone is
called castration-resistant prostate cancer (CRPC).

Prostate cancer that responds to treatment to lower testosterone is called castration-sensitive prostate cancer (CSPC).

Cancer That Has Not
Spread

If your doctor determined that you
have non-metastatic castration-resistant prostate cancer (nmCRPC):

  • Your prostate cancer is no longer
    responding to medical or surgical
    treatments that lower testosterone
  • Even though your testosterone is at
    low levels (50 ng/dL or less), your
    prostate-specific antigen (PSA)
    levels continue to rise
  • Imaging scans show that your
    prostate cancer has not spread to
    other parts of your body

Cancer That Has
Spread

If your doctor determined that you
have metastatic castration-resistant
prostate cancer (mCRPC):

  • Your prostate cancer is no longer
    responding to medical or surgical
    treatments that lower testosterone
  • Even though your testosterone is at
    low levels (50 ng/dL or less), your
    PSA levels continue to rise
  • Imaging scans show that your
    prostate cancer has spread to other
    parts of your body

If your doctor determined that you
have metastatic castration-sensitive
prostate cancer (mCSPC):

  • Your prostate cancer can respond to
    medical or surgical treatments that
    lower testosterone
  • Imaging scans show that your
    prostate cancer has spread to other
    parts of your body

Where can prostate cancer spread?
In many cases, the cancer cells will most likely travel to the bones first.
Prostate cancer can also spread to the lymph nodes, bladder, lungs, liver, and
other organs.

Questions to ask
your doctor

Filling out this guide can
help you and your doctor
create a prostate cancer plan
that’s right for you.

Prostate Cancer Doctor Discussion Guide, Small
NEXT: Tests and Scans